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. 2000 Dec 4;192(11):1535–1544. doi: 10.1084/jem.192.11.1535

Figure 3.

Figure 3

Induction of CTLs by DCs loaded with killed melanoma cells. Purified CD8+ T cells are cultured for 3 wk with unloaded DCs (UL-DC) or DCs loaded with Me275 (L-DC). (a) T cells are tested in a 4-h chromium-release assay, using as targets immunizing Me275 cells and K562 cells as a control for NK activity (mean ± SE, n = 4), as well as (b) unrelated HLA-A201+ tumor cell lines, prostate cancer (LnCap) and breast cancer (1806). No CTLs are elicited when T cells are cultured with killed melanoma cells without the DCs (not shown).

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