Figure 3.

The STAT6^−/− mice did not exhibit a reduced DTH induced by sheep RBCs (SRBC). Wt (WT) and STAT6^−/− mice were sensitized with the subcutaneous injection of 0.1 ml of 20% sheep RBCs. The increases in foot pad thickness of the wt or STAT6^−/− mice on a C57BL/6 background were measured 24 and 48 h after challenge by 20% sheep RBCs. Data presented are the mean values + SD of five mice per group and are representative of three independent experiments.