Table 1.
Serum IgG anti-dsDNA | Kidney deposition | ||||
---|---|---|---|---|---|
Mouse no. | μs | ELISA | Crithidia fluorescence | IgG | C3 |
U/ml | |||||
9116 | −/− | 0.08 | − | + | + |
9128 | −/− | 1.41 | + | +++ | +++ |
9383 | −/− | 1.74 | + | +++ | ++ |
9206 | −/− | 0.68 | + | +++ | + |
9397 | −/− | 0.53 | + | ++ | ++ |
9444 | −/− | 0.66 | + | +++ | +++ |
9461 | −/− | 0.08 | − | + | + |
9199 | +/− | 0.24 | − | ++ | ++ |
9332 | +/− | 0.10 | − | − | + |
9460 | +/− | 0.10 | − | + | + |
9288 | +/+ | 0.11 | − | + | + |
9338 | +/+ | 0.08 | − | +/− | + |
9486 | +/+ | 0.07 | − | +/− | + |
MRL/lpr | +++ | +++ | |||
NZB/W | +++ | +++ |
Kidney staining was monitored on anonymized samples with scoring ranging from − to +++. The staining, when apparent, was in the mesangium although mice 9128, 9206, and 9383 also revealed IgG deposition in the capillary wall.