Table 1.
IgG and C3 Deposition in Kidney
| Serum IgG anti-dsDNA | Kidney deposition | ||||
|---|---|---|---|---|---|
| Mouse no. | μs | ELISA | Crithidia fluorescence | IgG | C3 |
| U/ml | |||||
| 9116 | −/− | 0.08 | − | + | + |
| 9128 | −/− | 1.41 | + | +++ | +++ |
| 9383 | −/− | 1.74 | + | +++ | ++ |
| 9206 | −/− | 0.68 | + | +++ | + |
| 9397 | −/− | 0.53 | + | ++ | ++ |
| 9444 | −/− | 0.66 | + | +++ | +++ |
| 9461 | −/− | 0.08 | − | + | + |
| 9199 | +/− | 0.24 | − | ++ | ++ |
| 9332 | +/− | 0.10 | − | − | + |
| 9460 | +/− | 0.10 | − | + | + |
| 9288 | +/+ | 0.11 | − | + | + |
| 9338 | +/+ | 0.08 | − | +/− | + |
| 9486 | +/+ | 0.07 | − | +/− | + |
| MRL/lpr | +++ | +++ | |||
| NZB/W | +++ | +++ | |||
Kidney staining was monitored on anonymized samples with scoring ranging from − to +++. The staining, when apparent, was in the mesangium although mice 9128, 9206, and 9383 also revealed IgG deposition in the capillary wall.