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The effects of H-D-Pro-Phe-Arg-CMK on the clotting of plasma preabsorbed with bacteria. Human plasma samples, in the absence or presence of H-D-Pro-Phe-Arg-CMK (50 μg/ml final concentration), were incubated with strains SR11B, CsgA, or CsgB for 15 min. Bacteria were separated from plasma by centrifugation and the resulting supernatants were analyzed by the aPTT (A) or the PT (B) test. Data represent means ± SD of three experiments, each done in duplicate.
