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. 2000 Nov 20;192(10):1415–1424. doi: 10.1084/jem.192.10.1415

Table 2.

Quantification of Fibrin Deposition in Rat Lungs

Animal Control SR11B SR11B +H-D-Pro-Phe-Arg-CMK
% % %
1 2.3 87.7 18.2
2 3.1 60.1 19.1
3 3.4 71.8 19.9
4 2.1 87.1 23.1

Eight rats were infected with SR11B bacteria, from which four were treated with buffer or H-D-Pro-Phe-Arg-CMK. Noninfected animals injected with buffer alone served as controls and four animals in each group were analyzed. The ratio of the area containing fibrin deposition versus total area was determined by electron microscopy in six randomly chosen lung tissue sections from each animal. Fibrin deposition in vessels was not subtracted. The P value for the difference in fibrin deposition induced by SR11B in the absence or presence of H-D-Pro-Phe-Arg-CMK is <0.001.