Table 3.
Molecular Bases for Partial Deficiencies of C4A and C4B in the Normal Caucasian Population
| C4AQ0 | C4BQ0 | Total | ||||
|---|---|---|---|---|---|---|
| n | Percent | n | Percent | n | Percent | |
| Gene deletion | 36 | 12 | 15 | 5. | 51 | 17 |
| Mono-L | 3 | 1.0 | 15 | 5.0 | 18 | 6 |
| Mono-S | 33 | 11.0 | 0 | 0 | 33 | 11 |
| Gene mutation | 2 | 0.67 | 0 | 0 | 2 | 0.67 |
| Gene conversion | 2 | 0.67 | 40 | 13.3 | 42 | 14.0 |
| C4A-C4A | (40) | (13.3) | ||||
| A3-A3 | (30) | (10.0) | ||||
| A3-A2 | (8) | (2.67) | ||||
| Others | (2) | (0.67) | ||||
| C4B-C4B | (2) | (0.67) | ||||
| Total | 40 | 13.3 | 55 | 18.3 | 95 | 31.6 |