Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Expression of Bcl-XL does not restore normal cytokine production in CD28−/− T cells. Activated DO.11 WT (black bars) or DO.11 CD28−/− GFPhigh T cells (expressing control virus [white bars] or Bcl-XL virus [hatched bars]) were generated as described in the legend to Fig. 3. These cells were then cultured with OVA peptide (1 μg/ml) and mitomycin C–treated APCs in 24-well plates. After 12 h of restimulation, supernatants were harvested and analyzed for IL-2, IL-4, and IL-5 by ELISA.
