Figure 6.
Proliferation of naive T cells from mice reconstituted with stem cells infected with Bcl-XL virus. Naive CD4+ T cells isolated from the lethally irradiated mice reconstituted with bone marrow stem cells infected with control or Bcl-XL virus (see Fig. 5) were cultured with mitomycin C–treated APCs and a range of OVA peptide in 96-well plates. Plates were pulsed with [3H]thymidine for 6 h on days 1 and 2 of activation, and the incorporated radioactivity was measured.