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. 2000 Jun 19;191(12):2171–2182. doi: 10.1084/jem.191.12.2171

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Comparison of kinetics of serum clearance of IgA2m(1) and IgA2m(2) in C57BL/6 (W.T.) and ASGR^−/− knockout mice. Radiolabeled IgA2m(1) (A) or IgA2m(2) (B) was injected into the tail vein of C57BL/6 or ASGR^−/− knockout mice. At the indicated time points, the IgA remaining in the blood was determined as described in the legend to Fig. 3. The amount of TCA-soluble material present in the blood at the different times is shown in the insert. Each data point represents the mean ± SD of three mice.