Table 3.
Hemodynamic Parameters of Venules Studied: BK2r−/− Mice
| Mouse genotype (treatment) | No. of venules | Venule diameter | Centerline velocity | Calculated wall shear rate |
|---|---|---|---|---|
| μm | mm/s | s−1 | ||
| Wild-type (saline) | 11 | 28.0 ± 2.1 | 1.7 ± 0.1 | 318.0 ± 47.1 |
| BK2r−/− (saline) | 7 | 28.7 ± 1.9 | 1.5 ± 0.1 | 257.0 ± 19.1 |
| Wild-type (IL-1β/DABK) | 13 | 26.9 ± 1.6 | 1.4 ± 0.1 | 273.7 ± 25.2 |
| BK2r−/− (IL-1β/DABK) | 25 | 30.0 ± 0.8 | 1.4 ± 0.1 | 239.1 ± 9.5 |
Mice received either saline (0.25 ml intraperitoneally) or IL-1β (5 ng intraperitoneally, 24 h) followed by DABK (2 h). Data are mean ± SEM.