Table 2.

IL-10–treated DCs Induce T Cells from μMT Mice to Secrete IL-4

Recipient:	Control mice	μMT mice
Injectedwith:	UntreatedDCs	UntreatedDCs	IL-10–treatedDCs
Exp. 1
1	305.4 ± 3.1	80.6 ± 3.1	305.9 ± 52.4
2	187.7 ± 0.8	Not detectable	242.8 ± 17.8
Exp. 2
1	593.3 ± 73.4	63.7 ± 35.6	318.5 ± 31.1
2	204.4 ± 8.3	45.3 ± 0.5	610.0 ± 52.3

Secretion of IL-4 (in pg/ml) by lymph node T cells. Untreated or IL-10–treated DCs from wild-type mice were pulsed in vitro with KLH (50 μg/ml) and injected into the fore and hind footpads of control or μMT mice. 6 d later, lymph node cells were harvested and cultured with 5 μg/ml KLH and the Il-4 content was assessed by ELISA. Exp. indicates the experiment number; the indented numbers refer to individual mice. Limit for detection is 31.25 pg/ml.