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NK T Cell Subsets Defined by CD1d: α-GalCer Tetramers and NK1.1
| Property | NK1.1+ tetramer positive | NK1.1+ tetramer negative | NK1.1− tetramer positive |
|---|---|---|---|
| TCR repertoire | Vα14/Vβ8.2 | Diverse | Vα14/Vβ8.2 |
| Selecting ligand | CD1d | ? (not CD1d) | CD1d |
| Coreceptor expression | CD4 or CD4−CD8− | CD8 or CD4−CD8− | CD4 or CD4−CD8− |
| Tissue preference | Thymus, liver | Spleen, bone marrow | Intestine, lymph node |
