Table 3.

Lack of Correlation between the Class of Antibody Produced by Red Pulp Plasma Cells and Their Life Span

Spleen code/ day assessed	CGG-specific IgG+ cells		CGG-specific IgG− cells		NP-specific IgG+ cells		NP-specific IgG− cells
	n/mm2	% BrdU+	n/mm2	% BrdU+	n/mm2	% BrdU+	n/mm2	% BrdU+
A/day 5	134	57	40	30	20	50	30	23
B/day 5	79	63	9	30	15	31	17	29
C/day 5	69	56	10	23	11	55	45	40
D/day 5	72	63	10	17	8	32	27	77
Median/day 5	76	63	10	27	13	32	29	35
E/day 6.5	20	38	2	20	4	31	3	13
F/day 6.5	71	50	10	33	12	6	6	37
G/day 6.5	9	38	2	21	2	25	2	17
Median/day 6.5	20	38	2	21	4	25	3	17
H/day 9	51	62	12	37	7	10	7	20
I/day 9	29	45	4	23	17	22	8	19
J/day 9	13	43	3	6	5	9	3	16
K/day 9	23	28	4	23	6	27	8	23
Median/day 9	26	44	4	23	7	16	8	20

The mice shown in this table were primed with CGG and boosted with NP-CGG. They were given a BrdU pulse between 72 and 96 h after immunization; the number of antigen-specific plasma cells and the proportions of these that had taken up BrdU during the pulse were assessed on the day after immunization indicated in the leftmost column.