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. 2000 Oct 2;192(7):1069–1074. doi: 10.1084/jem.192.7.1069

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Induction by LL-37 of migration of (A) and Ca²⁺ flux in (B) human monocytes. (A) The migration of monocytes (10⁶ cells/ml) was assessed by chemotaxis assay using 5-μm uncoated membranes. Spontaneous cell migration (without LL-37) was ∼30–50 cells per HPF. The average C.I. (mean ± SD) of triplicate wells is shown. *P < 0.05 when compared with chemotaxis medium alone (open bar). (B) Arrow indicates the time point at which LL-37 was applied to the cells.