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. 2000 Oct 2;192(7):1069–1074. doi: 10.1084/jem.192.7.1069

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Chemotaxis of human neutrophils (A) and CD4 T lymphocytes (B) in response to LL-37. The cell migration was assessed by chemotaxis assay with the use of uncoated (A) or fibronectin-coated (B) 5-μm membranes. The results are presented as the average C.I. (mean ± SD) of triplicate wells. *P < 0.05 when compared with spontaneous cell migration (chemotactic medium alone). Neutrophils and CD4 T cells were used at a concentration of 10⁶ cells/ml and 5 × 10⁶ cells/ml, respectively. Spontaneous neutrophil and T cell migration (without LL-37) was ∼30–50 and ∼30–40 cells per HPF, respectively.