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. 2000 Oct 2;192(7):1069–1074. doi: 10.1084/jem.192.7.1069

Table 1.

Checkerboard Analysis of LL-37–induced Monocyte Migration

LL-37 in lower wells (μM) LL-37 in upper wells (μM)
0 1 10
0 40 ± 5 45 ± 6 44 ± 7
1 135 ± 15 50 ± 8 40 ± 6
10 495 ± 29 265 ± 5 95 ± 2*

Human monocytes were used at 106 per ml. LL-37 peptide at the specified concentrations was added to the lower wells of the chemotaxis chamber, and monocytes in the absence or presence of the specified concentration of LL-37 peptide were added to the upper wells of the chemotaxis chamber. The average (mean ± SD) of migrated monocytes of triplicate wells is shown as no./HPF. *P < 0.05 and P < 0.01 as compared with spontaneous monocyte migration (in bold type).