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. 2000 Nov 6;192(9):1223–1236. doi: 10.1084/jem.192.9.1223

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© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Association of recombinant ADAs with CD26/DPPIV on the AlNe human ADA-deficient T cell line. (A) Binding of wild-type human ADA (hum; filled circles) and wild-type mouse ADA (mus; open circles). (B) Binding of the m126–143 human–mouse ADA hybrid (filled circles) and the R142Q human ADA mutant (open circles). Circles, ADA activity; triangles, DPPIV activity.