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Leukocyte rolling velocities and L-selectin expression. Cumulative frequency of velocities of rolling leukocytes in wt and EP−/− mice with or without TNF-α treatment. wt data are shown for clarity and comparison from (reference 5). Significant reduction in rolling velocity in EP−/− with TNF-α treatment. ○, before the blockade of L-selectin shedding; •, 1–10 min after the blockade of L-selectin shedding. P < 0.01.
