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NO-dependent CFA-induced prevention of CNS infiltrate. Spinal cord tissue was harvested from the mice described in Fig. 4. Spinal cord tissue from a wild-type (A) or NOS2−/− mouse (B) preimmunized with CFA before MOG/CFA challenge. Panel C depicts disease scores from all of the animals studied in these groups. *P = 0.01, **P = 0.1.
