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. 2001 Apr 16;193(8):987–994. doi: 10.1084/jem.193.8.987

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Nonpolarized, Th1, and Th2 cells show different migratory capacity to lymph nodes, spleen, and inflamed tissues. CMTMR-labeled naive T cells were mixed with an equal number of CFSE-labeled nonpolarized (A), Th1 (B), or Th2 (C) cells and injected intravenously into syngeneic normal mice that were killed after 20 h. (A–C) Distribution of transferred cells in lymph nodes (left) and spleen (right). Percentages of CD3⁺CFSE⁺ and CD3⁺ CMTMR⁺ cells are indicated. One representative experiment out of five. (D) Absolute numbers of transferred cells recovered per 1,000 T cells in PECs (striped bars) and BAL (black bars). One representative experiment out of three. NP, nonpolarized.

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