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The TIE2Cre transgene activates the ROSA26R reporter allele and results in β-galactosidase activity in brain (Br), kidney (Ki), liver (Li), axillary LNs (LN), spleen (Sp), and thymus (Th), revealed by blue X-Gal staining (original magnification: ×100). Brain sections were 30 μm thick while all others were 10 μm. By way of example, thick and thin arrows in the spleen section indicate some larger vessels and arterioles, respectively.
