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. 2001 Jul 2;194(1):1–12. doi: 10.1084/jem.194.1.1

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© 2001 The Rockefeller University Press

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(a) Skin of the indicated donors were grafted on the back of the indicated recipient mice according to the protocol described in Materials and Methods. Graft rejection was controlled daily. Each dot represents a single recipient. This graph shows a representative result of four independent experiments. (b) LMP-7^−/− mice and wild-type littermates (129/Ola background) were immunized with wild-type or LMP-7^−/− splenocytes. CTL activity was tested after in vitro stimulation on LMP-7^−/− and wild-type concanavalin A blasts, RMA, and RMA-S cells as described in Materials and Methods. This graph shows a representative result of three independent experiments.

(a) Skin of the indicated donors were grafted on the back of the indicated recipient mice according to the protocol described in Materials and Methods. Graft rejection was controlled daily. Each dot represents a single recipient. This graph shows a representative result of four independent experiments. (b) LMP-7^−/− mice and wild-type littermates (129/Ola background) were immunized with wild-type or LMP-7^−/− splenocytes. CTL activity was tested after in vitro stimulation on LMP-7^−/− and wild-type concanavalin A blasts, RMA, and RMA-S cells as described in Materials and Methods. This graph shows a representative result of three independent experiments.