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. 2001 Jul 2;194(1):1–12. doi: 10.1084/jem.194.1.1

Table 3.

Correlation between Observed and Predicted Cleavages Preferentially Performed by c20S and i20S Proteasomesa

Source MHC restriction Influence of IFN-γ Sequence Reference
▾ NAPIL STLPETTVVRRRGRSPR
HbcAg 141–151 HLA-Aw68 + 14
▿ RGVQI ASNENMD AMDSRTLELR
Influenza A NP H2-Db + 35
▾▾ LMY DM YPHFMPTNL GPSEKR
LCMV pp89 H2-Ld + 8
▾▿ KIM RTE RPQASGVYM GNLTAQ
LCMV NP H2-Ld + 16
▾ YKISKL VNIRNCCYI SGNGAE
Adeno E1B H2-Kb + 13
▾ TGSTAVPYGSF KHVDTRLQ
RUI HLA-B51 20

aCleavages performed at comparable amounts by c20S and i20S proteasomes are not indicated. HBcAg, hepatitis B core antigen; ▾, i20S preference; ▿, c20S preference.