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Histological analyses of Listeria-infected mouse livers confirms the dominant role of IL-18 and TNF in primary immune responses to Listeria infection. Displayed are frozen sections from the livers of Listeria-infected Balb/c mice treated with the mAb combinations indicated and stained with either GR1, F4/80, CD4, CD8, or isotype control (data not shown) mAbs as described in Materials and Methods.
