Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2001 Aug 6;194(3):355–364. doi: 10.1084/jem.194.3.355

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

In vivo treatment with rIL-18 delays worm expulsion and suppresses Ag-specific IL-13 secretion independently of IFN-γ. T. muris–infected IFN-γ KO mice were injected with rIL-18 (white bar) or PBS (black bar) daily for 14 d. (A) Worm burdens were assessed at day 18 p.i. and MLN cells were stimulated in vitro with T. muris Ag (B and C) or LPS (D and E). Supernatants were analyzed by sandwich ELISA for the presence of (B) IL-4, (C) IL-13, (D) IL-12p40, and (E) IL-18. Results represent the mean value of 4–5 mice per group ± SEM. *Significantly different from PBS-treated control. P < 0.05.