Figure 6.
Attenuated positive selection of H-Y TCR+ T cells in zap-70 −/ − mice expressing ZAP-70(Y319F) or ZAP-70(Y315F). H-Y TCR+ thymi (top) or lymph nodes (bottom) from ZAP-70(Y319F)+ zap-70 −/ − (A) or ZAP-70(Y315F)+ zap-70 −/ − (B) female mice were analyzed for CD4 and CD8 expression. Cells shown represent the H-Y TCR+ population as defined by T3.70 staining. Average thymocyte number isolated for each genotype is represented in Table .