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. 2001 Aug 20;194(4):519–528. doi: 10.1084/jem.194.4.519

Figure 2.

Figure 2

Figure 2

Figure 2

Reduced survival of mice deficient in IL-17R signaling. (A) IL-17R KO, IL-17R+/−, or control mice (n = 10 each group) were challenged with intranasal K. pneumoniae and survival was recorded every 12 h. To confirm that the reduced survival phenotype was due to a lack of IL-17R signaling and not due to a developmental defect, 6–8-wk-old IL-17R KO mice or C57BL/6 mice infused with AdIL-17R Fc (Western blot of IL-17R/Fc fusion protein depicted in B) or a control virus were challenged with intranasal K. pneumoniae and survival was recorded every 12 h (C; n = 10 each group).