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. 2001 Oct 15;194(8):1123–1140. doi: 10.1084/jem.194.8.1123

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Extensive gene regulation in wt macrophages by IFN-γ and Mtb: extent of synergy. Numbers in bold face to the sides of the Venn diagrams report the total number of genes induced or suppressed (P ≤ 0.05) by IFN-γ, Mtb, or their combination. Numbers within the sectors tally the genes regulated uniquely or in common by these stimuli. The largest subsets of regulated genes were those that were only induced or suppressed by IFN-γ and Mtb acting synergistically. Instances in which IFN-γ and Mtb had opposite effects are omitted for clarity.