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. 2001 Oct 15;194(8):1123–1140. doi: 10.1084/jem.194.8.1123

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Genes directly related to inflammation or immunity are overrepresented among induced genes and among highly regulated genes. Genes regulated (P ≤ 0.05) in response to the stimuli named at the top of each graph were classified according to whether their products are directly related to immunity and inflammation (e.g., cytokines, chemokines, and metalloelastases versus ribosomal proteins, homeobox factors, and unannotated sequences), then binned according to the fold change in their expression. Black circles correspond to genes with fold change values >1. White squares indicate genes with fold change values <1 (suppression), represented as the inverse.