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. 2001 Oct 15;194(8):1123–1140. doi: 10.1084/jem.194.8.1123

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Differential regulation of macrophage gene expression by viable Mtb versus heat-killed Mtb or polystyrene beads. Numbers in bold face to the sides of the Venn diagrams report the total number of genes induced (A and C) or suppressed (B and D) (P ≤ 0.05) by each of the three particles alone (A and B) or in the presence of IFN-γ (C and D). Numbers within the sectors tally the genes regulated uniquely by a given particle or in common with one or both of the others. The largest subsets of regulated genes were those that were only induced or suppressed by viable Mtb alone or with IFN-γ.