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. 2001 Oct 15;194(8):1151–1164. doi: 10.1084/jem.194.8.1151

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Serum immunoglobulin levels and numbers of IgM and IgG3 secreting cells in mice having undergone RAG-2 deletion at birth. Immunoglobulin levels in the sera of mice in which RAG-2 had been deleted at birth were measured by ELISA at the age of 8 wk (A) and 17 wk (B). Numbers of IgM and IgG3 secreting cells in the spleen and BM (one femur) of individual 8-wk-old mutant mice and littermate controls were determined by ELISPOT (C). Dashes indicate geometric means.