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. 2002 Jun 3;195(11):1491–1497. doi: 10.1084/jem.20011793

Figure 5.

Figure 5.

Self-specific CD4 CD8α+βTCRαβ+ iIELs protect SCID.C57Bl/6 recipients of splenic CD4+CD45RBhiTCRαβ+ T cells from colitis. Pathology scores of individual male (□) and female (○) SCID.C57Bl/6 recipients of CD4CD8α+β iIELs expressing an HY/Db-specific transgenic TCRαβ, and splenic CD4+CD45RBhiTCRαβ+ T cells derived from male donors. Significant (P < 0.05) protection of male recipients was observed.