Table 2.
MPP+ levels, μg/gm striatum
|
|||
---|---|---|---|
90 min | 120 min | 240 min | |
WT | 3.33 ± 0.35 | 1.95 ± 0.38 | 0.44 ± 0.06 |
PARP−/− | 3.03 ± 0.35 | 2.12 ± 0.28 | 0.40 ± 0.13 |
MPP+ levels were determined at the times indicated after treatment with MPTP. Data are the means ± SEM, n = 3 for each value. No significant difference exists in MPP+ levels (two-way ANOVA) between PARP−/− or WT.