Figure 5.
Resident corneal CD11c+ cells upregulate expression of MHC class II after surgical inflammation. The center of normal uninflamed corneas, corresponding to areas procured for transplantation, contains numerous DCs (arrow heads) interdigitating between epithelial cells (arrows) as seen by TEM (A). These cells express CD11c (B), but uniformly fail to express MHC class II (Iab) antigens (C). Within 24 h of surgery, these DCs begin to coexpress Iab (D). Original magnifications 7,500× (A); 400× (B–D).