Figure 6.
CD11c+ cells migrating out of cultured corneal explants have modest allostimulatory capacity. Corneal explants were placed in culture, and the nonadherent cells harvested and stained for CD11c expression; representative data from 3 d-cultured explants shown (A). 105 cells harvested from BALB/c (allogeneic) or C57BL/6 (syngeneic) corneal explants kept in culture for 1, 3, or 6 d were used as stimulators for 2 × 105 C57BL/6 splenocytes in MLRs; splenic cells were used as control stimulators (B). Data demonstrate modest allostimulatory capacity by corneal cells cultured for 3 d or longer.