Figure 2.
PAF suppresses the induction of DTH. Mice were injected with cPAF (50 to 5,000 pmol) or exposed to UV radiation (10 kJ/m2) 5 d before immunization with C. albicans. 9 d later, the mice were challenged with Candida antigen. DTH was measured 24 h after challenge. The background response (negative control) was measured in mice that were not immunized but were challenged. The positive control was measured in mice that were immunized and challenged. Results are expressed as means ± SEM. An asterisk (*) indicates a statistically significant difference (P < 0.01) from the positive control (two-tailed Student's t test, n = 5). A representative experiment is shown; this experiment was repeated three times with similar results.