Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1999 May 17;189(10):1639–1648. doi: 10.1084/jem.189.10.1639

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Tg schematic. The mIgM heavy chain Tg is depicted. The DNA directing secretion (μs) and the transcription termination site (pA_s) have been deleted. V_H186.2 is the rearranged heavy chain V(D)J segment. E indicates the heavy chain intronic enhancer. Much of the switch region has been deleted; a small region of residual switch region is indicated.