FIG. 2.

Examples of FISH signals in semispread diploid yeast interphase nuclei which were used to determine the relative positions of chromosomal regions by measuring the two homologous (solid lines in panel a) and four homologous (broken lines in panel a) distances (see also reference 50). Equally colored dots (red-red and green-green) denote homologous chromosomal regions. (b) Both pairs of homologous signals associated. (c) One pair of nonhomologous signals associated. (d) Association of NOR-linked loci (green) is brought about by the fusion of nucleoli. The arrow denotes the single fused nucleolus. Blue, DAPI-stained chromatin.