Table 1.

Treatment Conditions in Steps of Behavioral Intervention for Experimental Group

	Treatment Steps1
Treatment Variables	− 4	− 3	− 2	− 1	0	+1	+2	+3	+4
Number of Scheduled Counseling Sessions/Week	3	3	3	2	2	2	Patient Selects 1, 2, or 3 Sessions/Week
Number of Methadone Take-Home Doses/Week2	0	0	0	0	0	0	1	2	3
Methadone Dosing Hours At Clinic3	Split Dose; Attends Clinic Twice/Day		Clinic Staff Selects Hours; Attends Once/Day				Patient Selects Hours; Attends Once/Day
Medication Dose4	20% Decrease	No Change	20% Decrease	Clinic Staff Selects Dose			Patient Selects Dose

¹Patients start at step 0 with a methadone dose of 55 mg. Each step is two weeks in duration and movement up or down depends on results of urine testing and adherence to scheduled counseling.

²Patients can earn up to 3 take- home doses per week and can choose which day to use them.

³If patient selects medication timing, hours to choose from becomes wider as the subject progresses in the steps (i.e. 9:00 to 19:30 in Step + 4). If clinic selected, hours are more restricted and less convenient. If split, patient must come to the clinic two times each day for full methadone dose.

⁴Patient selected methadone doses allow the patient to increase 5 to 10 mg over the next two weeks, up to a total dose of 80 mg; clinic selected doses changes may or may not be made in Step −1 and fixed reduction occur in Steps −2 and −4.