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. 2001 Nov 19;194(10):1541–1547. doi: 10.1084/jem.194.10.1541

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Copyright © 2001, The Rockefeller University Press

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Figure 5. — CCR4 and CTACK-dependent reduction of ear swelling in a cutaneous DTH reaction. Thy1.1 congenic recipients were treated with anti-CTACK mAb or the isotype control before the adoptive transfer of immunized Thy1.2⁺ donor LN cells. Recipient or control mouse ears were stimulated by local application of DNFB. Swelling induced by transferred CCR4^−/− but not by wild-type immune T cells is blocked with a mAb against CTACK. Background swelling of DNFB treated recipients without donor cells has been subtracted (mean ± SEM of seven experiments).