Figure 2.
The CD8+ T cell compartment does not expand in JNK1−/− mice during the primary LCMV infection in comparison to JNK2−/− and JNK+/+ mice but equivalent number of CD8+ T cell are noted 60 d later. JNK+/+, JNK1−/−, and JNK2−/− mice were injected intraperitoneally with LCMV ARM 2 × 105 PFU. Uninfected spleen cells and spleen cells 7 (D7) or 60 d (D60) postinfection were stained for CD4 and CD8. Data represent average values obtained from three animals per group and are representative of two independent experiments. Values written in the dot plots indicate the percentage of CD8+ T cells and the percentage of CD4+ T cells