Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2002 Apr 1;195(7):801–810. doi: 10.1084/jem.20011481

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2002, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 3. — The number of virus-specific CD8⁺ T cells and CD4⁺ T cells is lower in JNK1^−/− mice than in either JNK2^−/− or JNK^+/+ mice after LCMV infection. JNK1^−/−, JNK2^−/−, and JNK^+/+ mice were injected intraperitoneally with LCMV ARM, 2 × 10⁵ PFU. 8 d after infection, spleen were processed and stimulated for 5 h in vitro with virus-specific peptide GP aa 33–41, NP aa 396–404, GP aa 61–80, or NP aa 309–328. Cells were then stained for surface CD4 or CD8 and intracellular IFN-γ molecules. The number of virus-specific T cells was calculated from the number of total spleen cells obtained per animal. Data represent average values obtained from three animals per group and are representative of two independent experiments. (A) CD8⁺ T cells; (B) CD4⁺ T cells. *P < 0.05 #P = 0.052 when compared with JNK^+/+.

Figure 3. — The number of virus-specific CD8⁺ T cells and CD4⁺ T cells is lower in JNK1^−/− mice than in either JNK2^−/− or JNK^+/+ mice after LCMV infection. JNK1^−/−, JNK2^−/−, and JNK^+/+ mice were injected intraperitoneally with LCMV ARM, 2 × 10⁵ PFU. 8 d after infection, spleen were processed and stimulated for 5 h in vitro with virus-specific peptide GP aa 33–41, NP aa 396–404, GP aa 61–80, or NP aa 309–328. Cells were then stained for surface CD4 or CD8 and intracellular IFN-γ molecules. The number of virus-specific T cells was calculated from the number of total spleen cells obtained per animal. Data represent average values obtained from three animals per group and are representative of two independent experiments. (A) CD8⁺ T cells; (B) CD4⁺ T cells. *P < 0.05 #P = 0.052 when compared with JNK^+/+.