Figure 2.

Representative photomicrographs of hematoxylin and eosin stained intestinal tissues from 129SvEvRAG2^−/− mice that were reconstituted with purified CD4⁺ T cell subsets and/or infected with H. hepaticus as outlined in Fig. 1. (A–G) Colon sections from a control RAG2^−/− mouse (A) and from mice that received; H. hepaticus only (B), H. hepaticus and CD4⁺CD45RB^lowCD25⁺ T cells (C), CD4⁺CD45RB^high T cells only (D), CD4⁺CD45RB^high T cells and H. hepaticus (E), CD45RB^highCD4⁺ T cells plus CD4⁺CD45RB^lowCD25⁺ T cells and H. hepaticus (F), or CD45RB^highCD4⁺ T cells plus CD4⁺CD45RB^lowCD25⁻ T cells and H. hepaticus (G). (H–J) Cecum sections from a control RAG2^−/− mouse (H) and from mice that received; H. hepaticus only (I), or H. hepaticus and CD4⁺CD45RB^lowCD25⁺ T cells (J). Original magnification: ×50.