Table II.
Correlation between Jβ and Vα Usage among CW3-specific TCRs
| Gene segment usage in theCW3-specific αβ TCR repertoirea | ||||
|---|---|---|---|---|
| Vα3 | Vα4 | Vα8 | All Vα's | |
| Jβ 1.1 | 1.6 (3) | 4.1 (3) | 3.0 (2) | 8.7 (8) |
| Jβ 1.2 | 0.3 (1) | 21.0 (19) | 21.1 (16) | 42.4 (36) |
| Jβ 1.3 | 0 | 1.0 (2) | 5.9 (3) | 6.9 (5) |
| Jβ 1.4 | 10.0 (9) | 0 | 3.0 (1) | 13.0 (10) |
| Jβ 2.3 | 10.1 (9) | 0.4 (1) | 4.0 (2) | 14.5 (12) |
| Jβ 2.4 | 0 | 0.7 (1) | 0 | 0.7 (1) |
| Jβ 2.5 | 1.8 (2) | 0 | 1.2 (3) | 3.0 (5) |
| Jβ 2.7 | 0 | 1.0 (2) | 10.0 (6) | 11.0 (8) |
| All Jβ's | 23.9 (24) | 28.1 (28) | 48.1 (33) | 100 (85) |
a
The repertoires of CW3-specific αβ TCR clones identified in the study were combined, with the repertoire of each of the six mice weighted equally. The values represent the percent of clones in the combined repertoire that used each combination of Jβ and Vα gene segments. The numbers in parentheses indicate the number of different TCR nucleotide sequences (out of a total of 85) that were identified for each Jβ and Vα gene combination.