Figure 3.

Exploration of the memory phenotype and of the TCRβ repertoire of MLN αβ⁺ CD4⁺ cells of nude and euthymic mice. (a) MLN CD4⁺ cells from a nude mouse express the phenotype of memory cells, in contrast with comparable cells from an euthymic mouse. Cells were triply labeled with anti-TCRβ, anti-CD4, and anti-CD45RB mAbs. (b) The TCRβ repertoire of MLN DP cells from a nude mouse shows the gaussian-like profile characteristic of polyclonal populations (top), whereas that of SP CD4⁺ cells is oligoclonal (middle), in contrast with that of comparable cells from an euthymic mouse (bottom).