Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2003 Apr 7;197(7):907–918. doi: 10.1084/jem.20021366

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2003, The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 7. — CD1d expressed on bone marrow–derived cells are critical for the negative selection of NKT cells. 10⁷ bone marrow-derived cells from WT, Tg, and CD1dKO mice were transferred into lethally irradiated recipient mice (980 rad) by intravenous injection. After 10 wk, spleen and liver lymphocytes from bone marrow chimera were isolated and analyzed by flow cytometry. (a) Absolute NKT cell numbers of liver lymphocytes and splenocytes from each group of bone marrow chimeras. (b) IL-4 production by liver lymphocytes and splenocytes from each group of bone marrow chimeras. 10⁶ liver lymphocytes and splenocytes from indicated group of mice were cultured in the presence of 100 ng/ml of α-GalCer for 48 h. IL-4 levels in the supernatant were detected by ELISA.