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. 2003 Jun 2;197(11):1427–1439. doi: 10.1084/jem.20022059

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Copyright © 2003, The Rockefeller University Press

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Figure 1. — Soluble UL16 does not block ULBP-mediated cytotoxicity. Daudi cells expressing MHC class I and ULBP1 were used as targets in cytotoxicity assays using human NK cells, at the indicated effector/target ratios. Class I⁺/ULBP1⁺ Daudi targets were preincubated with the anti-ULBP1 Fab, M291, a control Fab, the UL16LZ protein, or a control LZ protein (RANK ligand-LZ), before the addition of effector cells. Individual data points are calculated from the averages of triplicate samples. The results shown are representative of three experiments using three separate donors.