Table II.
Half-maximal (EC50) Lymphokine mRNA Response of BMMCs to Ag
| Gene | Ag concentration (ng/ml)a | nb |
|---|---|---|
| MIP-1α | 1.1 ± 0.5 | 4 |
| IL-4 | 1.1 ± 0.3 | 3 |
| IL-2 | 1.2 ± 0.3 | 3 |
| MIP-1β | 1.3 ± 0.6 | 4 |
| M-CSF | 1.7 ± 0.3 | 5 |
| MCP-1 | 1.9 ± 0.4 | 4 |
| IFN-γ | 3.6 ± 0.4 | 3 |
| IL-13 | 5.4 ± 0.3 | 5 |
| TNF-α | 5.6 ± 0.7 | 5 |
| MIP-2 | 8.9 ± 1.2 | 4 |
| LIF | 9.8 ± 1.8 | 4 |
| IL-6 | 10.4 ± 2.7 | 5 |
| IL-10 | 11.7 ± 2.3 | 3 |
| IL-3 | 14.3 ± 2.2 | 3 |
The Ag (DNP-HSA) concentration for half-maximal response (EC50) was calculated from the data shown in Fig. 2. Data is the mean of all experiments with standard error. Data is arbitrarily grouped.
a
Ag concentration is expressed in ng/ml and is the concentration required to see a half-maximal response (EC50).
b
n is the number of experiments done for each lymphokine and used in calculation of the EC50.