Table I.
Microhemodynamic Parameters in Control Postcapillary Venules and Tumor Blood Vessels
| Blood vessel type |
Diameter | Mean velocity |
Wall shear rate |
Wall shear stress |
|---|---|---|---|---|
| μm | μm/s | s−1 | dyne/cm3 | |
| Control | 18.5 ± 3.5 | 705 ± 58 | 292 ± 28 | 7.3 ± 0.7 |
| Tumor, in general | 19.4 ± 3.8 | 348 ± 243a | 159 ± 128a | 4.0 ± 3.2a |
| Tumor, hot spots | 18.0 ± 1.8 | 435 ± 338 | 193 ± 149 | 4.8 ± 3.7 |
Mean values ± SD are shown; microhemodynamic parameters were assessed in control blood vessels (n = 4 animals with tumor-free skinfold chambers), regular tumor blood vessels (n = 6 animals), and in tumor blood vessels representing hot spots of eEPC recruitment (n = 5 animals).
a
*, P < 0.05 versus control.