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. 2003 Jun 16;197(12):1657–1666. doi: 10.1084/jem.20021546

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Copyright © 2003, The Rockefeller University Press

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Figure 7. — fAβ-induced recruitment of monocytes into the peritoneum is CD36 dependent. (A) CD36^+/+ or CD36^−/− mice were injected intraperitoneally with 100 μg fAβ. 24 h later, the peritoneal cells were harvested by lavage and the number of total cells counted was and differential cell counts were performed on 500 Heme3-stained cells per mouse (C). fAβ lead to recruitment of monocytes in CD36^+/+ (n = 10) but not CD36^−/− (n = 8) mice. Injection of carrier alone (PBS with 1 mg/ml BSA) did not induce significant monocyte recruitment. (B) CD36^−/− and CD36^+/+ mice injected with 1 mg zymosan recruited equivalent amounts of monocytes after 24 h. Each data point is the average ± SEM of results from the indicated number of mice (n) per genotype. *, P < 0.005.